Fluorescent Nanodiamonds for Tracking Single Polymer Particles in Cells and Tissues

Fluorescent Nanodiamonds for Tracking Single Polymer Particles in Cells and Tissues

Analytical Chemistry (2023)

This article presents a novel method for the long-term imaging and tracking of polymer nanoparticles within biological systems using fluorescent nanodiamonds (FNDs). Unlike conventional fluorescent dyes, FNDs do not bleach or blink, enabling continuous tracking in cells and liver tissues. The study demonstrates how FNDs, embedded within polymer nanoparticles, can be used to visualize and understand the transport routes of these particles in cellular and tissue environments, highlighting FNDs' potential for biomedical imaging and environmental studies on nanoparticle behavior.