Drug Delivery and Quantum Sensing in HeLa Cells
ACS Appl. Mater. Interfaces (2022)
This study demonstrates the application of functionalized fluorescent nanodiamonds (FNDs) for simultaneous drug delivery and free radical detection in HeLa cells. By modifying FNDs with a diazoxide derivative, researchers achieved enhanced cellular uptake and sustained drug release, compared to free drugs. The unique quantum sensing capabilities of FNDs enabled real-time monitoring of the local drug response and free radical levels within cells. This dual functionality of FNDs offers a novel approach for targeted cancer therapy, providing a method to deliver therapeutic agents directly to cancer cells while monitoring treatment effects at the nanoscale.
