Nanoscale MRI in Sperm Cells

Nanoscale MRI for Selective Labeling and Localized Free Radical Measurements in the Acrosomes of Single Sperm Cells

ACS Nano (2022)

A nanodiamond-based relaxometry approach for precise detection of free radicals within the acrosomes of sperm cells, addressing limitations of traditional free radical detection methods. By employing diamond magnetometry for its sensitivity to magnetic fields affected by free radicals, the researchers could pinpoint the primary source of radical generation during sperm capacitation, particularly identifying NOX5 on the sperm head's plasma membrane.