Nanodiamond Detection in Biological Conditions

Nanodiamond Relaxometry-Based Detection of Free-Radical Species When Produced in Chemical Reactions in Biologically Relevant Conditions

ACS Sensors (2020)

Diamond magnetometry, employing nanodiamonds with nitrogen vacancy centers, offers nanoscale detection similar to T1 MRI relaxation. This method, effective in real-time free radical monitoring in chemical reactions, distinguishes spin noise from different species. It demonstrates high sensitivity within biological environments, achieving nanomolar detection limits, and marks progress towards label-free nano-MRI quantification in biological settings.