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Publication
Skin equivalents from PCL scaffolds and Matrigel, mimicking native tissue. These models effectively assess UVA damage and antioxidant performance, with tea polyphenols showing superior efficacy. T1 relaxometry enabled single-cell free radical tracking....
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Fluorescent nanodiamonds revealed real-time, significant increases in mitochondrial free radicals in cells exposed to UVB radiation....
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FSH induces mitochondrial free radical generation in human granulosa cells, with minimal oxidative damage, suggesting ROS doesn't mediate FSH ootoxicity....
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Granulosa cells are vital for fertility. We used quantum sensing to reveal mitochondria as major sites of free radical generation during oxidative stress, and that cGCs are more resistant than mGCs....
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Free radicals are crucial for sperm, but their source was unknown. Diamond magnetometry identified NOX5 as the primary radical generator during capacitation, providing clarity....
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Acetaminophen overdose causes liver damage via free radicals. Nanodiamonds precisely located these radicals in organelles, improving understanding of cellular toxicity....
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Macrophages, vital immune cells, regulate inflammation by differentiating into M0, M1 (pro-inflammatory), or M2 (anti-inflammatory) subtypes. Using diamond-based quantum sensing, we tracked free radical changes in their vesicles. We found significant differences in free radical generation among the three macrophage subtypes, with levels evolving over time....
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Diamond relaxometry detects subtle free radical changes in primary human dendritic cells, revealing diverse donor responses to stimulation/inhibition....