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Diamond magnetometry's relaxometry enables subcellular, real-time detection of short-lived free radicals in living cells and isolated mitochondria....
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Quantum sensing with antibody-coated fluorescent nanodiamonds precisely measured real-time mitochondrial free radical production during hypoxia-reoxygenation, revealing links to cellular redox status....
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Utilizing diamond magnetometry, real-time free radical generation in human umbilical vein endothelial cells (HUVECs) were compared under varying shear stress conditions, revealing flow-dependent radical production....
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Functionalized fluorescent nanodiamonds (FNDs) deliver a cancer drug (diazoxide derivative) to HeLa cells with sustained release and simultaneously detect resulting free radical generation locally using relaxometry....
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Fluorescent nanodiamonds safely track cell differentiation, enabling sensing of intracellular free radicals. This study demonstrated their use in tracing and assessing radical production in differentiating colon cancer cells....
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Diamond quantum sensing tracked free radicals in migrating cancer cells. It revealed complex redox regulation, with NOX2 inhibition decreasing radicals but increasing ROS and migration....
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Nanodiamond quantum sensing (T1 relaxometry) detected increased free radicals in Huntington's disease C. elegans muscles with polyglutamine expression, offering submicrometer localization in vivo....
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Huntington's disease involves PolyQ aggregation causing free radical increases. Nanodiamond relaxometry revealed these radicals colocalize with aggregates at autolysosomes, linking aggregation to their dysfunction....